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BreastCancer
 9/9/2010 Non-Hormone Treatments Can Relieve Hot Flashes In Women With Breast Cancer
Many women enduring hot flashes experience the heat, sweat and reddened upper body as an uncomfortable inconvenience. However, hot flashes can greatly diminish a woman's quality of life, disrupting sleep at night or causing embarrassment as she goes about her daily business. Hot flashes, called flushes in medical circles, occur commonly in women with a history of breast cancer...
9/9/2010 Prophylactic Surgeries Associated With Lower Risk Of Cancer For Women With BRCA1/2 Gene Mutations
Women at increased risk of breast and ovarian cancer because of inherited mutations of the BRCA1 or BRCA2 genes who had prophylactic mastectomy or salpingo-oophorectomy (removal of the fallopian tubes and ovaries) had an associated decreased risk of breast cancer and ovarian cancer, according to a study in the September 1 issue of JAMA...
9/9/2010 The Optimal Set-Up For Obtaining The Best Breast Scan Image With Minimal Radiation Dose To The Patient
A mathematical tool known as a Monte Carlo analysis could help improve the way X-rays are used for mammography and reduce the number of breast cancers missed by the technique as well as avoiding false positives, according to research published this month in the International Journal of Low Radiation...
9/9/2010 Immutep Announces Final Results In Phase I/II Chemoimmunotherapy Trial In Metastatic Breast Cancer
Immutep S.A. announced the publication of a clinical research paper showing that its lead product, IMP321, given with first-line paclitaxel achieved clinical benefit in 90 per cent of metastatic breast carcinoma (MBC) patients. Correlations were observed with both the patients' monocyte (i.e...
9/9/2010 PIP (Poly Implant Prosthese) Breast Implants - UK Test Results
The Medicines and Healthcare products Regulatory Agency (MHRA) has received encouraging results of UK testing on the silicone gel breast implants manufactured by the French company Poly Implant Prosthese (PIP). The tests found no evidence of genotoxicity (potential for cancer) or chemical toxicity of the filler material in the implants...
9/9/2010 Newly Developed Prediction Tool Helps Estimate Local Recurrence In Patients With Non-Invasive Breast Cancer
The decision regarding treatment following breast-conserving surgery for patients diagnosed with ductal carcinoma in-situ (DCIS) has long been an area of discussion and confusion for patients and physicians alike. While the mortality rates for DCIS remain low, the risk of local recurrence in the breast is high. Standard treatments following surgery include radiation therapy and hormone treatment...
9/9/2010 Acupuncture Helps Ease Side Effects And Symptoms Of Some Cancers
Recent studies have shown that acupuncture can help control a number of symptoms and side effects -- such as pain, fatigue, dry mouth, nausea, and vomiting -- associated with a variety of cancers and their treatments...
9/9/2010 Using PET/CT In The Detection Of Breast Cancer Metastases
About one-third of women diagnosed with early-stage breast cancer will have their cancer travel, or metastasize, to other parts of the body, with the bone being the most common site of initial detectable spread...
9/9/2010 'Basal-Like' Breast Cancer Does Not Originate From Basal Stem Cells
New research uncovers a case of mistaken identity that may have a significant impact on future breast cancer prevention and treatment strategies. The study, published by Cell Press in the September 3rd issue of the journal Cell Stem Cell, suggests that despite their "stem cell-like" characteristics, most aggressive breast tumors are not derived from normal mammary gland stem cells...
9/9/2010 Important Breakthrough In Origins Of Aggressive Breast Cancer
Researchers have made a major breakthrough in finding out how aggressive cancers originate, raising hope of novel targeted therapies for future breast cancer patients, according to a study published in the peer-reviewed journal Cell Stem Cell...
9/9/2010 Study: Preemptive Surgery May Help Prevent Cancer For Some Women
A study published in the Journal of the American Medical Association suggests that women with a gene mutation linked to breast and ovarian cancer face lower risks of developing such cancer after receiving mastectomies or having their ovaries removed, The Wall Street Journal reports...
9/9/2010 Breast Cancer Prognosis Prediction Tool: Microsoft Excel-Based Algorithm
Using readily available computer programs, researchers have developed a system to identify genes that will be useful in the classification of breast cancer. The algorithm, described in BioMed Central's open access Journal of Experimental & Clinical Cancer Research will enable researchers to quickly generate valuable gene signatures without specialized software or extensive bioinformatics training...
9/9/2010 Study Indicates Targeted Strategies Needed To Find, Prevent And Treat Breast Cancer Among Mexican-origin Women
Specific prevention and education strategies are needed to address breast cancer in Mexican-origin women in this country, according to a study at The University of Texas MD Anderson Cancer Center, which was published online in the journal Cancer...
9/9/2010 Roche Provides Update On FDA Application For T-DM1
Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that the U.S. Food and Drug Administration (FDA) issued a Refuse to File letter for accelerated approval for the company's trastuzumab-DM1 (T-DM1) Biologics License Application (BLA). As planned Roche will continue with its ongoing Phase III EMILIA registration study...
9/9/2010 Surgeons Impact Whether A Woman Gets Breast Reconstruction
When breast cancer surgeons regularly confer with plastic surgeons prior to surgery, their patients are more likely to have reconstruction, according to a new study led by researchers at the University of Michigan Comprehensive Cancer Center. Where a woman goes for breast cancer treatment can vary widely - ranging from small private practices to large hospital settings...
9/9/2010 The ASCO Post Publishes Multiple Perspectives On Outcome Of ODAC Meeting Regarding Bevacizumab In Advanced Breast Cancer
The ASCO Post captured initial reactions to the Oncologic Drugs Advisory Committee (ODAC) recommendation that the breast cancer indication for bevacizumab (Avastin) be revoked in interviews with ODAC voting members, breast cancer specialists, oncologists in private practice, third-party payers, and a patient advocate....
9/9/2010 Eisai Announces Extension Of FDA Review Of Drug Application For Investigational Agent Eribulin Mesylate
Eisai Inc. announced today that it has received notification from the U.S...
9/9/2010 Link Between High-Fat Diet During Puberty And Breast Cancer Risk Later In Life
Girls eating a high-fat diet during puberty, even those who do not become overweight or obese, may be at a greater risk of developing breast cancer later in life, according to Michigan State University researchers. The implications - that a high-fat diet may have detrimental effects independent of its effect to cause obesity - could drive new cancer prevention efforts...
9/9/2010 Swiss Breast Cancer Patient Becomes First In World To Receive Treatment Using Gated RapidArc From Varian Medical Systems
A 51-year-old breast cancer patient from Switzerland has become the first person in the world to be treated using Gated RapidArc®, which makes it possible to monitor patient breathing and compensate for tumor motion while quickly delivering radiotherapy during a continuous rotation around the patient...
9/9/2010 Preventive Surgeries Linked To Lower Risk Of Breast And Ovarian Cancer
Women with the inherited mutations of the BRCA1 or BRCA2 genes who had preventive (prophylactic) breast removal (mastectomy) or the removal of the fallopian tubes and ovaries (salpingo-oophorectomy) were found to have a significantly lower risk of developing ovarian and breast cancers, says a study published in JAMA (Journal of the American Medical Association), September 1st issue...
9/9/2010 Genentech Receives Refuse To File Letter From FDA For T-DM1
ImmunoGen, Inc. (Nasdaq: IMGN), a biotechnology company that develops antibody-based targeted anticancer products, announced that Genentech, a member of the Roche Group, announced its receipt of a Refuse to File (RTF) letter from the US Food and Drug Administration (FDA) for the accelerated approval of the Biologic License Application (BLA) for trastuzumab-DM1, or T-DM1, submitted in July 2010...
9/9/2010 Adult Mammary Stem Cells Identified And Isolated For The First Time In Mice, Potential For Breast Tissue Regeneration And New Cancer Drug Targets
For the first time, researchers at Fred Hutchinson Cancer Research Center have identified and isolated adult mammary stem cells in mice. Long-term implications of this research may include the use of such cells to regenerate breast tissue, provide a better understanding of the role of adult stem cells in breast cancer development, and develop potential new targets for anti-cancer drugs...
9/9/2010 Roughly One In Six Cancer Survivors Forgo Some Medical Care Due To Cost, Study Finds
AARP Bulletin: "Two years after undergoing a double mastectomy and chemotherapy so severe she was hospitalized in intensive care for several weeks, breast cancer survivor Denise Hicks should be following what her doctors call 'the plan,'" which includes additional medications and treatments. But she can't. "Hicks has health insurance but already reached her coverage limits...
9/9/2010 Genentech Provides Update On FDA Application For T-DM1
Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), announced the U.S. Food and Drug Administration (FDA) issued a Refuse to File letter for accelerated approval for the company's trastuzumab-DM1 (T-DM1) Biologics License Application (BLA). As planned, Genentech will continue with its ongoing Phase III registrational T-DM1 trial, EMILIA...
9/9/2010 24-hour Test Predicts Breast Cancer's Likely Response To Chemotherapy
A new test has been developed which can predict whether a breast cancer patient will respond to chemotherapy within 24-hours of starting treatment, thus sparing her unnecessary treatment and side effects, according to a study published in the medical journal Clinical Cancer Research...
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